Vasculitis is inflammation of the blood vessels. In certain forms of vasculitis, such as granulomatosis with polyangiitis (Wegener's granulomatosis), the nasal cavity is frequently affected. The cartilage of the nose may become chronically inflamed, which can result in damage the septum and lead to saddle nose deformities. The underlying disorder must be treated medically before attempting surgical correction. Patients in remission from their disorder can undergo rhinoplasty using standard techniques. Additional cartilage grafting from the ear or rib is frequently required.